TARGETED RNA SEQUENCING: REVOLUTIONIZING FUSION GENE DETECTION

RNA sequencing (RNA-Seq) has revolutionized transcriptome analysis, providing valuable insights into gene expression, transcript structure, and variation. However, the detection of rare or low-abundance expressed genes remains a challenge due to the vast size and complexity of the transcriptome. To overcome these limitations, targeted RNA sequenc

What is epitranscriptomic modification? RNA modifications, not limited to purine or pyrimidine bases, including N6-methyladenosine (m6A), 1-methyladenosine (m1A), 5-methylcytidine (m5C), 5-hydroxymethyl cytidine (hm5C), 5-formyl cytidine (f5C), 5-carboxy cytidine (ca5C), inosine (I), pseudouridine (Ψ), and 2′-O-methylation (Nm). RNA modificatio